Healthgevity
Healthgevity Resolve+ Capsules
Healthgevity Resolve+ Capsules
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- About the Brand
Aging is characterized by an increase in the concentration of inflammatory markers in the blood- stream, a phenomenon that has been termed “inflammaging”. The inflammatory response is beneficial as an acute, transient reaction to harmful conditions, facilitating the defense, repair, turnover and adaptation of many tissues. However, chronic and low-grade inflammation is likely to be detrimental for many tissues and for normal functions. Our team investigated various natural solutions targeting multiple influences of inflammaging. Resolve+ contains numerous compounds that have been found to reduce the inflammatory response by targeting a variety of mechanisms.
Acmella oleracea (“jambu”) is sourced from Sardinia, Italy and rich in alkylamides mainly represented by spilanthol. Its flowers are widely used in folk medicine to treat toothache due to tingling, numbness, and local anesthesia caused in the mouth. Acmella oleracea has been shown to be active in fatty acid amide hydrolase (FAAH) inhibition the enzyme responsible for the degradation of fatty acid amides and cannabinoid type 2 (CB2) activation. There are almost 100 studies suggesting the supportive potential for anti-inflammatory, antioxidant, and analgesic effects of Acmella. Studies reported in this review confirmed activities of Acmella, postulating that transcription factors of the nuclear factor-κB family (NF-κB) trigger the transcription iNOS and COX-2 and several other pro-inflammatory mediators, such as IL-6, IL-1β, and TNF-α.
Curcumin, a natural polyphenolic compound derived from turmeric (Curcuma longa L.), has been well documented to exhibit various health benefits. There have been many claims on the health benefits of curcumin on neurological, cardiovascular, lung, metabolic, and liver function, mainly through its anti-inflammatory and antioxidant properties. Despite its promising potential, the clinical application of curcumin has been limited due to its low bioavailability.
To enhance curcumin absorption, we are the first to feature Theracurmin Super® 85X, a proprietary curcumin utilizing the latest technology that transforms standard curcumin into an amorphous structure. Theracurmin Super® 85X uses the latest technology to transform regular curcumin particles into a more bioavailable structure. This is done by splitting curcumin particles’ crystal structure amorphous, therefore, making it easily absorbed and bioavailable to maximize its supportive potential.
Tetrahydrocurcumin (4-HC) is the key bioactive derivative of curcumin, it’s also given credibility as the engine behind all that curcumin brings to the table. With a newfound ability to extract and isolate the compound, research has even seen tetrahydrocurcumin outperform its parent compound in several tests of its capabilities. Researchers have also confirmed that 4-HC attenuated pro-inflammatory indicators like interleukin-1, interleukin-6, TNF-⍺, and prostaglandin E2. After reviewing the data, we found many advantages to infuse tetrahydrocurcumin as CurcuPrime® stacked with Theracurmin Super® 85X into Resolve+.
Quercetin is a well-known studied dietary flavonoid ubiquitously present in various vegetables. Quercetin is known for its antioxidant activity in radical scavenging and anti-allergic properties characterized by stimulation of immune system, antiviral activity, inhibition of histamine release, decrease in pro-inflammatory cytokines, leukotrienes creation, and suppresses interleukin IL-4 production. Multiple studies have confirmed its supportive potential as an immune modulator and its ability to support a healthy inflammatory response. It can improve the Th1/Th2 balance, and restrain antigen specific IgE antibody formation However, chemical instability, poor water solubility and low bioavailability of quercetin greatly limit its applications which is why a phytosome technology which we feature in resolve is the preferred delivery system to overcome these limitations. This enhanced form of quercetin has been shown to be as much as 20 times better absorbed than other quercetin options.
Casperome® boswellia phytosome is a potent extract made from the resin of Boswellia serrata trees and is also referred as Indian frankincense. Boswellia extracts have been demonstrated to be effective in the management of various inflammatory response functions including those that occur in the bowel, joints, bones, respiratory airways and in the brain. The mechanism of action that involves the modulation of the natural inflammatory response both acting on prostanoid synthesis (mPGE2S) and protein degradation (caspases), and transcription factors (Nf-κB). We have selected Casperome® which is a highly standardized in boswellic acids to match the natural composition of boswellia, formulated with phytosome technology to achieve optimized absorption and has been validated by over 10 human studies.
Perilla frutescens is an annual herb belonging to the mint family (Lamiaceae). It is mainly produced in countries like China, Japan, India, Thailand and Korea. Recently, Perilla is gaining more attention because of its medicinal benefits and phytochemical contents. The functional compounds of Perilla Seed Extract are flavonoid Aglycons – polyphenols such as Luteolin, Apigenin, Chrysoeriol, and Rosemarinic Acid. Studies have shown that Perilla seed polyphenols regulate allergic and inflammatory response due to its 5-lipoxygenase inhibitory activity and suppression potential of histamine release from mast cells.
AstraGin® is a natural compound derived from the roots of two traditional Chinese herbs: Panax notoginseng and Astragalus membranaceous which contain astragaloside I, II, IV and ginsenoside Rb1. AstraGin® has been shown to provide full-spectrum gut support through enhanced absorption, microbiota and immune cell viability, and supporting a health. AstraGin® has been shown in numerous studies to increase the absorption of peptides, amino acids, fatty acids, vitamins, and phytonutrients by up regulating the absorption specific mRNA and transporters, such as SGLT1, CAT1, and GLUT4. Additionally, AstraGin® was shown to reduce intestinal inflammatory biomarker MPO, the pro-inflammatory cytokines IL-6, IL-17, and IL-1β in ulcerative colitis patients.
*This is a statement of nutritional support. This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases. Individual results may vary.
General Shipping Information
Orders over $75 ship FREE with Standard Shipping
Orders must total $75 before tax (and after any promotional discounts) to qualify. We do not ship internationally at this time.
In most cases, we are able to ship orders placed before 1:00 pm central time on the same day.
Estimated delivery time: 3-5 business days.
Pick Up Orders: pick-up orders placed before 2:00 are generally ready same day. However, we will contact you when the products are ready for pick up in our Bee Cave Alive + Well Store.
Texas Orders: local Austin orders are generally delivered next business day - without any additional fees. Most major Texas cities are also eligible for next business day delivery (call to learn if your city is eligible for next day delivery)
USPS Priority Shipping
Estimated delivery time: 3-5 business days.
2-Day and Overnight: Order must be placed by 12pm CST for processing on same day. Orders placed after 12pm CST on Thursday will ship on Friday and will be delivered on the following Monday (via Overnight) or Tuesday (via 2-Day). Orders placed after 12pm on Friday will ship on the following Monday. 2-Day and Overnight orders cannot be delivered on Saturdays or federal holidays. Not available for delivery to PO Boxes.
Standard Shipping: Orders shipped via standard shipping may be delivered to PO Boxes and APO/FPO/DPO addresses. Shipping carrier and method will be determined by Alive + Well's Shipping Department. Standard shipping time is 3-5 business days.
Shipments outside the continental US: 2-Day and Overnight shipping orders to Alaska and Hawaii are subject to an additional charge of $10.
Shipments to Puerto Rico can only be done via USPS; 2-Day and Overnight shipping options are not available.
Shipping Refrigerated Products : Our manufacturers formulate their probiotics to ensure their products retain viability until they reach the consumer. Probiotics that are recommended to be refrigerated remain so until the time of shipment, then shipped alongside an ice pack to ensure potency (Note: Ice pack will not arrive frozen, and product may not arrive cold). However, you may want to consider using 2-Day and Overnight shipping methods when purchasing probiotics to ensure maximum potency.
Orders placed on a Thursday-Sunday requiring cold shipping will not ship until the following Monday.
Shipping Address: A safe and accurate address for delivery must be provided at the time the order is placed. Once an order has shipped, Alive + Well is not responsible for lost or stolen packages confirmed to be delivered to the address as entered for the order. If the tracking indicates the package has been delivered, you would be required to place a new order.
AUTOSHIP ORDERS
When you subscribe for Autoship, you'll save 10% on future automatic order (select products do not include a discount on recurring orders). You can skip an order, change the frequency, pause your subscription, or cancel at any time. Your credit card will be billed and the order will be shipped on the same day the order is set to process. You can update your Autoship schedule or make any changes to the order in your online account. You can cancel this schedule at any time.
Additional discounts cannot be applied to autoship products.
Shopping is risk-free with our 30-day return guarantee*. If for any reason you are not satisfied with your purchase, simply send the unused portion back to Alive and Well within 30 days of purchase. Return postage is the responsibility of the customer. You will receive a full refund for the item(s) in the original form of payment. After we process your return, it may take several business days for the refund to appear on your credit card, depending on your financial institution.
*Select products are final sale.
Please note that we are only able to process returns for a maximum of 3 items per year.
Shipping and handling charges are non-refundable. For returns via mail, the product must include your full name, order number and be carefully packaged. Return postage is the responsibility of the customer.
Once your return has been received, a refund will be issued within 14 days in the original form of payment, and an email confirmation will be sent.
Please return shipments to the following address:
Alive + Well Returns3944 Ranch Road 620Bldg 8, Ste 100Bee Cave, TX 78738
